Therapeutic Area

Neuro Inflammation
As a pre-clinical Immunology CRO we test therapeutics that limit and control inflammation within the central nervous system.
There is a growing literature on the contribution of the immune response to neurodegenerative diseases. We have designed assays that test novel therapeutics aimed at preventing or blocking the inflammatory cytokines/chemokines generated by microglial cellsand aspects of microglial function such as phagocytosis.
Example of key assays designed to test therapeutics that modulate immune function of microglial cells
  • Microglia: iPSC derived Microglia phagocytosis, iPSC derived Microglia, cytokine (Inflammasome) /chemokine release
  • Neuron: Neurite out growth

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