Modulation of inflammatory or anti-inflammatory M1/ M2a-d function

Macrophages are highly plastic and can differentiate into a range of activated phenotypes driven by external signals under various disease conditions. Therapeutic driven modulation of macrophage phenotype has the potential to modulate many different disease types where macrophage play a key role in either driving or regulating disease. We present here a range of macrophage polarisation conditions that model macrophage phenotypes found in different disease states run in 96 well or 384 well screening mode.