Services

Drug Discovery

Navigate the complex immunology landscape with confidence through our comprehensive drug discovery CRO services. We provide end-to-end support from early target validation through to candidate selection, using human-relevant multicellular assays and biomarker strategies that predict clinical success.

Our assays are designed to test all types of therapeutics including Small Molecules, Biologics, Vaccines, Cell Therapies and Gene Therapies.

How we can support your Drug Discovery Process

TARGET VALIDATION SERVICES

We validate targets in primary human cells and established cell lines, assessing target expression profiles through flow cytometry or qPCR under various disease relevant stimulation conditions. Thereafter, tailored in-vitro functional assays, specific to the cell type and target, are used to confirm the impact of target inhibition or engagement. This is achieved using gene knockout functional assays or direct pathway inhibition with known modulators.

LEAD OPTIMISATION SERVICES

We provide expert support for your lead optimisation program, by customising or using standard assays to answer key questions on target engagement, mode of action, selectivity and identifying robust translational biomarkers in primary human cells from healthy and diseased donors. By integrating multi-cellular assay systems, we aim to replicate the complex in vivo cell-to-cell interactions seen in disease, helping you advance drug candidates with greater confidence.

PREDICTIVE IMMUNOTOXICOLOGY SERVICES

We deliver predictive immunotoxicology services that give an indication of potential pre-clinical drug safety liabilities. Our assays evaluate cytokine release and detect off-target immune events, helping to de-risk drug development programs and improve the likelihood of clinical success.

CLINICAL BIOMARKER SERVICES

Robust biomarkers are essential for the success of any drug discovery program, offering clear indicators of target engagement and measurable biological responses to therapy. We deliver expert preclinical biomarker development and non-regulatory clinical biomarker services to support early Phase I and Phase II clinical trials. With extensive experience handling clinical samples, we offer a full range of cellular, analytical, and functional biomarker assays that demonstrate both drug-target engagement and clinical efficacy.

Drug Discovery Tool

Find the right immune assay for your therapeutic area, modality and target using our interactive Drug Discovery Tool.

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