B cell
Autoimmunity Assays
- Antibody production (Total IgG)
- Memory B cell Antibody Isotypes
- Naïve B cells Isotype switching
- B cell proliferation/activation/cytokine secretion
- Antigen presentation
![](https://www.nexusbioquest.com/app/uploads/2023/02/Group-11277.png)
Tonsillar re-aggregate model
Tonsils are a secondary lymphoid tissue rich in B cell subsets and the specialized, anatomically restricted T follicular helper (Tfh) subset of CD4 T cells. Tonsils provide an accessible source of cells for those interested in B cell immunology, Tfh biology and vaccine development. The tonsillar cell re-aggregate model provides functional insight into human germinal center biology, allowing measurement of key features including naive B cell differentiation, plasma cell/plasmablast differentiation, and antibody production.
![](https://www.nexusbioquest.com/app/uploads/2024/05/Tonsil-schematic-1024x197.png)
![](https://www.nexusbioquest.com/app/uploads/2024/05/B-cell-phenotype-2-1024x489.png)
![](https://www.nexusbioquest.com/app/uploads/2024/05/B-cell-prolif-1-1024x512.png)
![](https://www.nexusbioquest.com/app/uploads/2024/05/B-cell-Ig-1-1024x317.png)
![](https://www.nexusbioquest.com/app/uploads/2023/03/Micro-1.png)
Drug Discovery Tool
Find the right immune assay for your therapeutic area, modality and target using this interactive Drug Discovery Tool.