# Nexus Bioquest
> We provide comprehensive pre-clinical and non-regulatory clinical services spanning target validation, mechanistic studies, and translational research, ensuring every aspect of your immune-therapeutic development is supported by scientific excellence. Through our dedicated CRO services, we transform complex immunological questions into clear, actionable data that drives informed decision-making and accelerates your pre-clinical drug discovery programs from concept to clinic.


Important notes:
- Contract research organisation (CRO) specialising in immunology 
- Providers of drug discovery and bespoke assay design services. 
- Specialists in therapeutic areas such as immuno-oncology, autoimmunity, inflammation and hypersensitivity, and neuro inflammation. 


---


## Core Services
- [Drug Discovery] (https://www.nexusbioquest.com/services/drug-discovery/): Services include target validation, lead optimisation, predictive immunotoxicology and clinical biomarker expertise.
- [Bespoke Assay Design] (https://www.nexusbioquest.com/services/bespoke-assay-design/): Services include consultation, study design and study execution. 


—


## Therapeutic Areas
- [Immuno-oncology in vitro assays] (https://www.nexusbioquest.com/therapeutic-areas/immune-oncology/): We provide services to test novel immuno-oncology therapeutics that use the immune system to prevent, control or destroy tumours.
- [Auto immunity in vitro assays] (https://www.nexusbioquest.com/therapeutic-areas/autoimmunity/): We provide Autoimmune related services to test therapeutics that modulate or re-educate harmful self-directed immune responses.
- [Inflammation and hypersensitivity in vitro assays] (https://www.nexusbioquest.com/therapeutic-areas/inflammation/): Test therapeutics that limit and control chronic or acute inflammation caused by various agents such as microbes, allergens (birch, grass, house dust mite, food), aging and autoantigens.
- [Neuro inflammation in vitro assays] (https://www.nexusbioquest.com/therapeutic-areas/neuro-inflammation/): We provide pre-clinical services that test therapeutics aiming to limit and control inflammation within the central nervous system.


—


## Case Studies


- [3D Tumour Models for Immune Screening] (https://www.nexusbioquest.com/3d-tumour-killing-models-tool-for-screening-immune-therapeutics/): Tool for screening immune therapeutics; bench mark therapeutics in an immune check point inhibitor (Pembrolizumab) sensitive assay or ADCC.
- [Are you fully exploring the potential of NK mediated therapeutics?] (https://www.nexusbioquest.com/are-you-fully-exploring-the-potential-of-nk-mediated-therapeutics/): See how NK cell driven ADCC is being developed for oncology and autoimmunity; targeting either unwanted tumour cells or autoreactive immune cells.
- [Therapeutic Targeting of Neutrophil Netosis and Phagocytosis] (https://www.nexusbioquest.com/therapeutic-targeting-of-neutrophil-netosis-and-phagocytosis/): We present data from NETosis and phagocytosis assays which can be used to determine how a therapeutic alters neutrophil function.


---


## Insights & Resources


- [Reflections from IO360 – Insights and Innovation in Immuno-Oncology] (https://www.nexusbioquest.com/reflections-from-io360-insights-and-innovation-in-immuno-oncology/): The event highlighted the next wave of innovation in IO, from new emerging cancer immunotherapy data, as well as new tools that help accelerate therapeutic development.
- [Neutrophils: First Responders, Fierce Defenders, and Key Targets in Disease] (https://www.nexusbioquest.com/neutrophils-first-responders/): The role of neutrophils in disease is becoming increasingly understood and targeting these cells with therapeutics at the site of inflammation could benefit patients in many inflammatory diseases.
- [IND-Supporting Offering] (https://www.nexusbioquest.com/ind-supporting-studies-nexus-bioquest/): We deliver high-standard studies designed to support regulatory submissions like INDs and similar filings.


---


## Company


- [About](https://www.nexusbioquest.com/about/): Providing expertise and innovative solutions to accelerate your immune-therapeutics into the clinic.
- [Contact](https://www.nexusbioquest.com/contact-us/): Our team of scientists are experts in advancing immune focused therapeutic programs.


---


## Technical Information
> This file follows the [llms.txt specification](https://llmstxt.org/) to help AI systems understand and attribute our content.


Format: Markdown (.txt)  
Scope: Entire website  
Last updated: 2026-02-11


---


## Attribution
> Website maintained by [Appeal Digital](https://appeal.digital)


© copyright Nexus BioQuest Limited 2026